Cheque Drops was not quite a popular bodybuilding drug till the time Mike Tyson placed his teeth on Evander Holyfield’s ears during a boxing bout, it is believed that Tyson’s aggression was because of the fact that he was under the influence of Cheque drops.

The molecular formula of Cheque Drops is C₂₀H₃₀O₂ and its molecular weight is 302.455 g/mol at the base. It has an active life of approximately 2-4 hours and is a 7,17-dimethylated derivative of nandrolone. The methyl group at C-7 inhibits 5-alpha reduction of the compound, which means that this compound will not get converted to a weak metabolite in androgen receptive tissues, on the same line as nandrolone. Moreover, Mibolerone does not bind with body proteins and can therefore exist in a free state in the blood.

Cheque drops is an oral steroid and needs to be administered sublingually. The recommended dose of Cheque drops is 200-250 mcg per day for a period no longer than two weeks. Results from doses can be seen within 30 minutes after administration of this steroid. One of the greatest benefits of Cheque drops is that testosterone levels in the body get normalize without the need of running any type of post cycle therapy, which means that users do not need antiestrogens such as Clomid and Nolvadex.

JC Romero

Romero alleged that it was not him, but the manufacturers and distributors of nutritional supplements who were accountable for his positive drug test.

From NYdailynews.com:

Suspended Phillies reliever J.C. Romero is suing the makers and distributors of nutritional supplements that he says are responsible for his positive steroid test last August.

The 27-page lawsuit, filed Monday in New Jersey Superior Court in Camden County, blames the product 6-OXO Extreme for traces of androstenedione found in the pitcher’s urine on Aug. 26, 2008.

The numerous counts in the lawsuit include negligence, intentional misrepresentation and consumer fraud. The four defendants named are GNC, Vitamin Shoppe, Ergopharm and Proviant Technologies.

Romero was tested positive for androstenedione and handed over a suspension of 50 games but was permitted to participate in spring training session without being paid.

Anavar, which is also known as Anvar and Oxandrolone, is one of the very few steroids that have been able to maintain their goodwill. This is simply because Anavar is not only a potent steroid but also a safe and affordable steroid. Categorized as a Schedule III (non-narcotic) controlled substance under the Anabolic Steroids Control Act of 1990, Anvar is admired by professional sportsmen to stay high on name, fame, and recognition by delivering record-shattering performances on a continuing basis.

One of the biggest reasons why Anavar is preferred over other anabolic steroids and performance enhancing drugs is because it does not lead to estrogen and other side effects such as high blood pressure, water retention, gynecomastia, and acne unless abused to a significant extent. Moreover, Anavar is relatively mild on the natural endocrine system when compared to other steroids in the market.

Benefits are easy to attain when users make use of Anavar in doses of 20-25 mg/day (for men) and 5-15 mg/day (for women). In order to optimize benefits of Anavar during a steroid cycle, it can be stacked with Winstrol, Equipoise, Primobolan, and Trenbolone. It is however important to note that this anabolic steroid should not be abused else it can lead to side effects such as edema, acne, male pattern baldness, and insomnia.

The research that was conducted by the University of Southern California’s Keck School of medicine was released at the American College of Neuropsychopharmacology’s (ACNP) annual conference.

From News.bio-medicine.org:

“Most people use anabolic steroids to enhance their physical performance, but they deny that steroids may be addictive,” noted lead researcher Ruth Wood, PhD, Professor of Cell and Neurobiology at USC. “Unlike other commonly abused drugs, the primary motivation for steroid users is not to get high, but rather to achieve enhanced athletic performance and increased muscle mass. The complex motivation for steroid use makes it difficult to determine the addictive properties of anabolic steroids in humans. Our goal was to create an experimental model of addiction where athletic performance and other reinforcing effects are irrelevant.”

Wood’s study is among the first to examine the potential for anabolic steroid addiction. The research was modeled after well-established methods used to study highly addictive drugs, such as cocaine and heroin. Hamsters were implanted with small cannulas for self-administration of commonly abused steroids into their brains. The animals then spent four hours per day in a chamber with access to two delivery mechanisms. When the hamster operated the active mechanism, he received 1 microgram of testosterone, or one of several commonly abused steroids: nandrolone, drostanolone, stanozolol, or oxymetholone.

It was suggested by the study that coaches and athletes must be aware of the addiction aspect besides other possible risks of using anabolic steroids.

Anadrol

Categorized as a Schedule III drug under the Anabolic Steroid Control Act of 1990, Anadrol is considered by many steroid users as the most powerful oral steroid that can help them attain “unthinkable” body strength and muscle mass gains besides proving as a wonder drug when it comes to improving transportation of more of oxygenated blood. This anabolic steroid is also effective for protecting joints, which are often a common problem with sportsmen visiting the gym and undergoing strenuous workouts.

The chemical name of Oxymetholone is 17ß-hydroxy-2-(hydroxymethylene)-17-methyl-5a-androstan-3-one and its chemical formula is C₂₁H₃₂O₃.

Anadrol is also effective for improving the count of erythropoietin, the hormone, which is involved in the production of red blood cells. Anadrol users can easily expect an increase in body weight by as much as 10-15 pounds in less than 2 weeks.

The recommended dose of Anadrol is 1-5 mg per kg of body weight. This performance enhancing drug is not meant for individuals having an existing allergy to Anadrol or its ingredients and breastfeeding or pregnant women. When used in contravention or absence of medical advice, use of Anadrol can lead to side effects such as nausea, vomiting, stomach aches, and lack of appetite, insomnia, and diarrhea.

Lupus

The biological rationale as to why large doses of corticosteroids (steroids) administered over several weeks can be of great help to lupus patients was revealed by researchers at the UT Southwestern Medical Center.

From News-Medical.Net:

Unlike the anabolic steroids athletes sometimes use illegally to bulk up muscle, corticosteroids are routinely used to treat inflammation in lupus patients. The drugs, however, can cause undesirable side effects including weight gain and acne when taken over long periods of time.

In a study published in a recent issue of Nature, researchers at UT Southwestern and other institutions show in blood cells that giving very high doses of intravenous corticosteroids early and frequently in the course of the disease is more effective at killing the cells that drive lupus than giving the standard limited intravenous steroids followed by high doses of oral corticosteroids over a period of months. The cells used came from lupus patients as well as from animal models of lupus.

Dr. Marilynn Punaro, professor of pediatrics at UT Southwestern and co-author of the study, remarked that administration of high doses of steroids in the preliminary stages and on a regular basis could greatly help in high steroid doses at a later point of time.

Albuterol

Also known as Albuterol sulfate, this drug can easily be labeled as a performance enhancing drug. It helps professional sportsmen, particularly those participating in weight categories, to lose body weight in a short span of time without bringing them close to side effects. Albuterol is second to none when it comes to treating sportsmen with breathing disorders such as asthma besides promoting a sense of well being.

The recommended dose of this miracle drug is 2-4 mg, 3-4 times a day. It is very important to note here that no two doses of Albuterol can be taken together in case one is missed. This drug is not to be used by individuals having an existing allergy to Albuterol or any of its ingredients and is not to be used by pregnant or breastfeeding women.

Albuterol users should be careful while handling it and it should not be incinerate or puncture or brought close to the eyes. Albuterol doses must be in complete accordance with medical guidance else Albuterol abuse can lead to severe health complications such as dry mouth, dizziness, excessive sweating, and tremor. In case any abnormality is experienced by the user, the use of Albuterol should be immediately discontinued and the same should be reported to a qualified medical practitioner.

Also known as Clenbuteral and Spiropent, Clenbuterol (Clen) is one performance enhancing drug that is in a league of its own. Clenbuterol is second to none when it comes to reducing excess body weight in a short span of time without coming in contact with any side effect. Furthermore, Clen is equally effective in enhancing aerobic abilities and improving the levels of muscle function, muscle mass, body strength, and endurance.

The selective Beta-2-symphatonimetric agonist (Clen) has the chemical formula of C₁₂H₁₈ CI₂N₂O and the chemical name of -Amino-alpha-[(tert-butylamino)methyl]-3,5-dichlorobenzyl alcohol Monohydrochloride.

Clenbuterol is admired by professional sportsmen as a pre-contest drug, which is highly effective for them especially for those participating in weight categories such as swimming, boxing, and bodybuilding. It is also used to treat individuals afflicted with asthma.

The advised dose of Clenbuterol is 100-140 mcg per day for men and 50-100 mcg/day for women. It is important to note here that this performance enhancing drug is not to be used by individuals having an existing allergy to Clenbuterol or any of its ingredients.

Clenbuterol use must be initiated only after a qualified medical advice as Clen abuse can lead to severe health complications such as excessive sweating, nausea, palpitation, limb tremor, tachycardia, and insomnia.

This study by Associate Professor of Medicine E. Rand Sutherland, MD, MPH and his colleagues at National Jewish Health was published in an issue of the American Journal of Respiratory and Critical Care Medicine.

From Sciencedaily.com:

The study at National Jewish Health sought to understand why glucocorticoids, commonly called steroids, might be less effective in overweight and obese asthma patients. Dr. Sutherland and his colleagues enrolled 45 nonsmoking adults, 33 of whom had asthma, and measured the response of cells in the blood and the lungs to the steroid dexamethasone.

Steroids interfere with inflammatory signaling pathways by raising the level of a molecule known as MAP kinase phosphatase-1 (MKP-1). When the researchers applied the steroid dexamethasone to cultures of the participants’ blood cells, they found that steroids did not increase MKP-1 as effectively in overweight and obese asthmatics when compared to lean asthmatics. Dexamethasone increased the levels of MKP-1 by 5.27 times in cultured blood cells from lean asthma patients, whereas MKP-1 levels in overweight and obese asthmatics increased by only 3.11 times, a 41 percent smaller response. The heavier a person was the less their cells were likely to respond to dexamethasone. This negative relationship between weight and response to steroids did not occur in participants who did not have asthma.

Dr. Sutherland and his colleagues conducted a long-term study to examine the effects of steroid resistance in clinical terms among overweight and obese asthma patients besides clarifying the signaling pathways involved.

Testosterone Cypionate is rated higher than Testosterone enanthate, another derivative of testosterone. This is primarily because the cypionate version is superior to the enanthate version in terms of active life and half life. Having a chemical structure of 4-androstene-3-one, 17beta-ol and ester molecular weight of 132.1184 g/mol, this long acting and single ester testosterone derivative has an anabolic/androgenic ratio of 100:100 and available in oral and injectable forms.

It can be detected over a period of 3 months and promotes improvements in terms of performance, endurance, body strength, and muscle function along with regulating the production of testosterone in the body.

Testosterone cypionate, the anabolic steroid, can be used in weekly doses of 300-2000 mg by men but not for a period exceeding 6-8 weeks at a stretch. This testosterone compound is generally stacked with Dianabol, Primobolan, Equipoise, and Clenbuterol. In case the level of estrogen formation exceeds the normal, antiestrogens such as Nolvadex and Clomid can be used. The use of these ancillary drugs can help in restoring the natural production of testosterone besides helping testosterone cypionate users stay away from gynecomastia and fluid retention.