Archive for November, 2010

A form of substance abuse is growing increasingly to worry health care experts and worldwide governments. Abuse of legally sold dietary supplements – vitamins, minerals, herbals, and homeopathic remedies – that can be sold without prior approval for safety and effectiveness.

However, users of these drugs should realize the fact that many heralded dietary supplements have the potential for harm, particularly when taken in large doses and/or in different combinations with one another or with medically prescribed prescription drugs.

From NYTimes.com:

A new federal law requires supplement manufacturers to report serious adverse effects to the Food and Drug Administration, but it depends on consumers to call in reactions. Experts say most consumers are unlikely to relate health problems to a supplement they assume to be safe, and even if they do, they may be reluctant to report an adverse effect from a self-medicated substance.

Not so for Michael Alexander of San Francisco. In September, he wrote to Kaiser Permanente that a vitamin supplement he had regularly bought from the Kaiser pharmacy caused years of leg cramps, eventually diagnosed by a neurologist as vitamin B6-induced neuropathy. The supplement had 100 milligrams of B6, or 50 times the recommended daily amount. The ill effect developed even though Mr. Alexander cut each tablet in four parts and took ”only” 25 milligrams daily.

According to a 2002 Harris poll, 70 percent of adults in the United States take vitamins, minerals, herbs or other supplements. Their use of supplements has been increasing, fed by the belief that they can make people feel better, give them greater energy, improve health and prevent and treat disease. Although some supplements are beneficial, others may or may not be. Others may be downright dangerous. Even so-called safe supplements can be hazardous in too large amounts or the wrong combinations.

David Schardt, senior nutritionist for the Center for Science in the Public Interest, a watchdog group in Washington, recently said consumers fail to realize that there is a huge difference between dietary supplements, homeopathic remedies, and over-the-counter medications.

Drostanolone enanthate, popularly known as Masteron enanthate, is one of the very few performance enhancing drugs that command great admiration among sportsmen on steroids looking to excel in every professional competition.

The safe-to-use and easily accessible anabolic steroid is a popular performance enhancing drug (PED) among professional sportsmen, primarily because of the fact that it does not aromatize to estrogen while stimulating dramatic muscle mass, body strength, and performance gains. This easily means that sportsmen taking this PED do not need ready supplies of antiestrogens such as Clomid and Nolvadex to inhibit excess estrogen formation and prevent side effects such as gynecomastia and fluid retention.

Drostanolone enanthate is characterized by an ester length and concentration that makes it one of the best choices for improving the blood levels along with achieving optimum steroid use benefits in as short as 4-6 weeks. The pre-contest drug is commonly administered in an injectable form though one can find oral version of the drug in the online world of anabolic steroids and performance enhancing drugs.

The steroid can be detected over a period of 3 months and has an active life of 7-8 days. The anabolic/androgenic ratio of Masteron enanthate is 62:25 and its standard dosage is 400-600 mg per week for men and 100-115 mg for women for a maximum period of 6-8 weeks at a stretch. The doses should not be altered at will else this can lead to side effects such as acne, oily skin, menstrual irregularities, hair loss, and enlargement of the clitoris. In order to optimize complete benefits during a steroid cycle, sportsmen can stack Drostanolone enanthate with Winstrol, Anavar, and Primobolan.

Bulking up with anabolic steroids can weaken and damage the heart along with increasing the odds of heart failure, according to a new study.

It was highlighted by the study findings that use of steroids can be more harmful than previously thought but there was no evidence to suggest that steroids have bad health effects.

From in.reuters.com:

Pope, who has studied anabolic steroids for over 20 years, said the drugs began to crop up in gyms around the country in the 1980s, and quickly flourished. Today, as many as two million Americans may have abused the controlled substances at one point or another.

“We may be seeing just the beginning of something that could become a huge public health problem,” Pope said.

With his colleagues, he advertised for weightlifters who could bench more than 275 pounds. That way, he got both steroid users and “clean” bodybuilders without having to disclose the study’s purpose, which could have biased the results.

The researchers measured the recruits’ heart function using ultrasound. Among the 12 steroid users, 10 turned out to have hearts that pumped less blood into the body than they should. In contrast, only one of the seven non-users had this problem.

Complete magnitude of the problem may not declare itself until after 20 or 30 years, as per Dr. Harrison G. Pope of Harvard University, who worked on the new study, published in the journal Circulation.

If you have been avoiding anabolic steroids and performance enhancing drugs due to fear of hair loss, Dutasteride is one hair care drug that you need to know about. This treatment drug for loss of hair works effective for baldness induced by steroids or other medical reasons.

Dutasteride is an effective drug when it comes to shrinking the size of enlarged prostate in men, especially those on steroid cycles involving aromatizable steroids or harsh performance enhancing drugs. The 5α-reductase inhibitor interferes with the 5α-reductase enzymes in order to facilitate the process of breaking down testosterone, which could have otherwise converted into DHT (Dihydrotestosterone).

Dutasteride has the molecular weight of 528.5 g/mol at the base and chemical name of 5α,17β-N-{2,5 bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1-ene-17-carboxamide. The active ingredient in Dutasteride tablets is dissolved in a mixture of butylated hydroxytoluene and mono-di-glycerides of caprylic/capric acid while the list of inactive ingredients includes gelatin, glycerin, and ferric oxide. The molecular formula of this hair care drug is C₂₇H₃₀F₆N₂O₂.

Dutasteride is considered by medical practitioners, all over the world, as one of the most reliable and safe drug for treating individuals afflicted with benign prostatic hyperplasia (BPH) in men with prostate enlargement. In addition to this, the drug is also considered to be of great importance when it comes to managing acute urinary retention (AUR) and inhibiting requirements for BPH related surgery procedures.

When used in daily doses of 0.5-1.0 mg with or without meals, Dutasteride demonstrates its true potential. The drug is, however, not recommended or prescribed to expecting or breastfeeding women due to probability of damage to the male fetus. It is recommended that you seek medical advice before you decide to buy Dutasteride online, without or with a prescription, as Dutasteride abuse could lead to health complications such as impotency, ejaculation complications, and gynecomastia.

Sportsmen, all over the world, trust human growth hormone (HGH) when it comes to delivering record-breaking performances without a fail. The fact that this performance enhancing drug is safe, effective, easily accessible, and yet cheap says it all for its unmatched success and popularity, especially in the last few decades.

HGH was originally developed as a drug for treating aging but soon gained prominence as a body building drug that has the potential to boost performance, body strength, and muscle mass in as short as 4-6 weeks. Available in varying forms – powder, injection, spray, and pills – human growth hormone is a protein (somatrophin) including 191 amino acids that treats deficiency of naturally produced HGH in the body, which is a common problem with growing age.

Human growth hormone is second to none when it comes to promoting improvements in terms of bone strength, brain function, and stress handling skills, exercise capacity, and muscle tissue repair. It is also beneficial for lowering the recovery time associated with intense workouts and is also useful for reducing sun-damage type wrinkles, total body fat, and LDL cholesterol. If that was not all, human growth hormone is equally effective in enhancing support functions of the human body such as body part integration, cell replacement, and muscle definition. Medically, HGH is prescribed to individuals afflicted with muscle wasting or cachexia and is also recommended to patients who have lost stamina significantly.

The standard dosage of human growth hormone (HGH) is 1-5 I.U. every day when administered via a 1 mL disposable syringe, preferably on stomach or arms and legs. The doses should not be altered at will else this could lead to HGH side effects such as nausea, insomnia, headache, fatigue, and edema.

Glucocorticoid-induced osteoporosis (OP) is better treated with Teriparatide, synthetic form of the human parathyroid hormone, than alendronate.

This finding was disclosed by a recent study in which researchers suggested that glucocorticoid-induced OP patients who are administered with teriparatide for 36 months had a greater increase in bone mineral density (BMD) and fewer new vertebral fractures than those treated with alendronate.

From Sciencedaily.com:

Glucocorticoids are steroid hormones that are naturally produced in the body or synthetically created compounds (drugs) used to reduce inflammation. These steroid drugs are used to control inflammation in patients with such autoimmune diseases as rheumatoid arthritis, systemic lupus erythematosus, and Crohn’s disease as well as inflammatory conditions such as asthma. Glucocorticoid-induced osteoporosis occurs when patients taking steroid medications such as prednisone, prednisolone, dexamethasone, and cortisone exhibit reduced bone mass and bone strength.

This 36-month, randomized, double-blind, controlled trial, led by Kenneth Saag, M.D., from the University of Alabama, was conducted at 76 centers located in 13 countries. A total of 428 patients between the ages of 22-89 with confirmed OP who had received greater than 5 mg/day of prednisone or equivalent for more than 3 months preceding screening were included. Research measures included changes in lumbar spine and hip bone, BMD, changes in bone biomarkers, fracture incidence, and safety.

The findings of this study are published in the November issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR).

If you are looking for a cheap alternative to Dianabol for redefining muscle mass, body strength, and performance improvements then Anadrol is one of the best oral steroids for you, especially when it comes to bulking.

The underground steroid, which is a Dihydrotestosterone (DHT)-derived compound, is better than performance enhancing drugs like Winstrol, Masteron, Anavar, Primobolan, and Proviron when it comes to deriving optimum benefits during a steroid cycle.

It is the US brand name for Oxymetholone, which is a highly potent oral androgen. Medically, Anadrol is used to provide significant relief to individuals afflicted with anemia. In the worlds of body building and other competitive sports, Anadrol is admired by sportsmen to stay close to dramatic body strength and performance gains in a very short time.

The use of this performance enhancing drug can lead to estrogen side effects such as gynecomastia and fluid retention and it is recommended that Anadrol users have ready supplies of antiestrogens such as Arimidex, Nolvadex, or Clomid. The standard dosage of Anadrol is 0.5-0.8 mg per pound of body weight per day, which means a daily dose of 50-200 mg per day. It is worth noting here that Anadrol doses should not be altered without medical guidance and only research grade Anadrol should be purchased else this could lead to side effects such as headaches, nausea, vomiting, stomach aches, lack of appetite, insomnia, and diarrhea.

Anadrol is not recommended to girls and women, especially pregnant and breastfeeding women, and also those having an existing allergy to Anadrol or any of its ingredients.

Use of potentially harmful steroids is soaring among young men wanting to improve their body image and online steroid imports should be banned, according to a recently submitted report by ACMD.

The recommendation was made after it was seen that there was an all-time high in the imports of anabolic steroids amid growing concern over their use by teenage boys and young men to improve their body image.

From Guardian.co.uk:

The ACMD’s chair, Professor Leslie Iversen, said steroids were now much too easily available: “If you search online you will see endless offers. The ACMD is the lone voice against this tide of promotion on the internet. We think [an import ban] would have a considerable dampening effect on demand. It may be difficult to enforce but it would act as a simple deterrent.”

Iversen said steroids were becoming a “big phenomenon” in Britain: “There is no question that the number using the drug for sporting reasons is now a minority. The real growth has come in young users who want to improve their body image.”

An ACMD report to the home secretary on anabolic steroids published today quotes the latest figures from the British Crime Survey, estimating that 50,000 people in the past year have used anabolic steroids for non-medical purposes, such as bodybuilding. More than 220,000 told the BCS they had used anabolic steroids.

But drug experts say these are probably underestimates of the numbers using anabolic steroids because many people will not openly admit to using the drugs, even in an anonymous self-report survey such as the BCS. Some needle and syringe exchange programmes for problem drug users have also reported an exponential rise in steroid injectors, according to the report.

Growing use of anabolic steroids, particularly among young men, was a worrying development, as per Iversen. It was suggested by the ACMD that anabolic steroids should remain a class C illegal drug that can be purchased on prescription from a pharmacist.

If the cost of Deca Durabolin is the biggest reason why you could not purchase it, NPP (Nandrolone Phenylpropionate) is a great alternative for you. This anabolic steroid is slowly but steadily gaining popularity as one of the safest, effective yet cheap performance enhancing drugs in the town today.

Nandrolone Phenylpropionate, popularly known as NPP, is used and admired by sportsmen on steroids and expecting to stay close to performance improvements and body strength gains. This premium quality yet cheap anabolic steroid is best summarized as a top class body building drug that allows sportsmen to deliver better than expected each time, every time without coming in proximity with steroid side effects.

NPP is medically used to treat anemia and has the unique potential of enhancing the production levels of red blood cells to a considerable extent. The steroid compound is also effective to enhance collagen synthesis in order to improve joint function besides alleviating joint pain.

The standard dosage of NPP is 350-700 mg per week for a maximum period of 6-8 weeks at a stretch. The steroid is commonly stacked with performance enhancing drugs such as Anavar, Dbol, Equipoise, and Winstrol but is not recommended with Anadrol and Trenbolone. The doses of Nandrolone Phenylpropionate should not be altered and the drug should only be purchased, after a medical advice, from a reputable online steroid pharmacy else side effects such as fluid retention, impotency, and abnormal weight gain can be experienced. Medical advice is highly recommended for individuals keen to take NPP and presently taking insulin, oral anticoagulants, adrenal steroids, or oral anti-diabetic agents.

Two OTC dietary supplements, Tren Xtreme and Mass Xtreme, which are popular among high school football players, contain steroids according to court papers filed by federal authorities.

The supplements are marketed as ”potent legal alternative to” steroids and manufactured by American Cellular Labs. It was found by the authorities that these supplements include illegal man-made steroids, also known as designer steroids.

From NYTimes.com:

The authorities said that Max Muscle, a walk-in supplement store with about 100 locations nation-wide, paid American Cellular Labs to be the exclusive retailer of these products, which could also be purchased on the Internet.

Maurice Sandoval, identified in the court documents as American Cellular’s chief executive, said in a telephone interview that he never personally sold steroids but declined to comment on whether the company had sold steroids. He said he sold the company last year but that a paperwork error kept his name on the company.

Someone who answered the phone Thursday at Max Muscle’s corporate office in Anaheim, Calif., said no one was available to comment on how many Max Muscle stores carried the American Cellular products. ”This is not our product,” said the man, who would not give his name and hung up.

On Thursday, the Web site of a Max Muscle outlet in Des Moines was offering a promotion of Tren Xtreme for free, but a salesman who answered the phone there said the store no longer sold the brand.

Travis Tygart, the head of the United States Anti-Doping Agency, declined to make any comments when asked about estimates for how many high school athletes had used the product.